We are an interdisciplinary research group that applies the concept of controlling proximity between molecules to regulate their interactions and downstream biological effects. We combines the techniques of synthetic chemistry, biochemistry, molecular biology, imaging and bioengineering to develop novel tools and molecules to study important biological questions and to develop novel therapies.
The current focuses in the lab include:
- Develop new strategies for spatiotemporal regulation of microRNAs and long non-coding RNAs.
- Engineering novel biological functions in mammalian systems using chemical and synthetic biology approaches.
We will apply these tools to study cancer biology and synaptic plasticity and develop new therapeutic strategies.